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BASIS
Pathogens such as viruses, bacteria, protozoa, amoebae, and even worms can be found in virtually all water supplies. Pathogens are known to cause diseases such as Cholera, Typhoid Fever, Diarrhoea, Dysentery, Legionellosis, and Gastroenteritis. Due to the pathogens, all water supplies must be disinfected before they can be considered potable or sometimes waste or cooling water must be disinfected before being re-useable or disposable. Disinfection kills or inactivates disease-causing micro-organisms in a water supplies and must provide a > 99.9% inactivation of e.g. Giardia lamblia cysts. Disinfectant maintains disinfection residual in finished water to prevent regrowth of micro-organisms.
The development of a fast, accurate and competitive technique for detection of pathogenic microorganisms is needed in water supplies but moreover in many areas of research, medicine, hospitals, food industries and industrial processes. Early detection of a pathogenic determinant allow for a short response time and thus a reduced exposure to the environment and could improve general safety and health. Traditional microbiological detection methods based on morphological or physiological parameters are often tedious and time-consuming.
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Automated Pathogen-DNA Analysis
Identification based on Realtime-PCR, is signifficantly faster, with similar or better results, although it required significant manual input. Thus, up to now pathogen detection on the routine basis was limited by manual sample handling.
For realistic field application automation with ultra-sensitve devices is more cost effective and reproducible.
Attophotonics detects pathogenic micro organisms via real time PCR based automated detection using methods for processing and analysis of sample material automating all individual process steps integrating the capture, collection and handling system. The system is free of manual handling for days to weeks.
PATENTS: WO03010278, FR2827873,.
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