SENSORS and ANALYTICS Attophotonics develops and manufactures sensor components and systems for biotechnological and chemical analysis: SENSORS POINT-OF-CARE DEVICES & MICROFLUIDICS AUTOMATED ANALYZERS . ELECTROCHEMICAL SENSORS Attophotonics manufactures sensor components using various thin and thick film technologies. Some products are shown below. Sensors are manufactured on request. Sensor Electrodes Layout glass chromium / gold aluminum oxide titanium / platinum polyimide platinum + Ag-ref. glass titanium platinum aluminum oxide titanium PCB - screen printed Ag / C / isolation PET - screen printed Ag / AgCl/ isolation and many more….

MICROFLUIDICS

Using polymer films as base material Attophotonics produces different types of microfluidic devices via

laser machining

hot embossing

REA-CHIPS

Like Attophotonics’ smart colors REA-chips are based on the patented nano-color technology. However, REA-chips detect analytes of medical importance. Binding of the substrate is indicated via (multi-colored) text or images – without requiring costly digital displays.

POC-REA-MICROFLUIDIC CHIP

Attophotonics’ novel point-of-care-microfluidic chip combines both the technologies shown above in a lateral-flow rapid test. It allows the analysis of small sample volumes within 3-5min at a sensitivity of <500 pg/ml. This product has been developed for a company in US. AUTOMATED ANALYZERS Attophotonics develops fully automated analytical robotic systems. Attophotonics has already developed various systems for customers all over the world.An automated robotic system for analysis and control of yeast and eukaryotic fermentation was developed and installed for Boehringer Ingelheim.An automated robotic system for pathogen-control of water supplies was developed for SAUR/France and was implemented e.g. in Paris North. Various other systems are run at universities for R&D applications. ANALYZER FOR SAUR FRANCE Pathogens such as viruses, bacteria, protozoa, amoebae, and even worms can be found in virtually all water supplies. Pathogens are known to cause diseases such as cholera, typhoid fever, dysentery, legionellaires’disease and gastroenteritis. Due to the pathogens, all water supplies must be disinfected before they can be considered potable and sometimes waste or cooling water must be disinfected before being re-used or disposed of. Disinfection kills or inactivates disease-causing microorganisms in water supplies. (A > 99.9% inactivation of Giardia lamblia cysts must be provided, for instance.) A fast, accurate and competitive technique for detection of pathogenic microorganisms was developed by Attophotonics for use in water supplies – and is now proprietary to SAUR/ France. NOTE: This robotic system is moreover applicable in many areas of research, medicine, hospitals, food industries and industrial processes. The know-how and the necessary technology are available via Attophotonics Austria. Automated Pathogen-DNA Analysis Identification is done based on automated cell-cracking combined with robotic Real Time-PCR. Detection is significantly faster and more sensitive in comparison to other techniques. Cells are opened by a novel technology based on electromagnetic pulse radiation and DNA as well as RNA is harvested and purified on site. Pathogen detection on the routine basis is no more limited by manual sample handling. In a realistic field application the ultra-sensitive devices are sensitive down to 3 cells / liter. Attophotonics detects pathogenic microorganisms via Real Time-PCR-based detection. All individual steps of sample processing and analysis are automated in an integrated capture, collection and handling system. The system is free of manual handling for days to weeks: PATENTS: US2004241828, ES2355748, AT486950, FR2827873,…